ALFASIGMA UK LIMITED
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Cash
—
Latest balance sheet
Net assets
£8.2m
+61.7% vs 2024
Employees
48
+6.7% vs 2024
Profit before tax
£4.2m
+922.8% highest in 5 filed years
Net assets
6-year trend · vs Industrials median
Accounts
6-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2020-12-31 | 2021-12-31 | 2022-12-31 | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|---|---|---|
| Turnover | — | £23,442,828 | £24,385,117 | £20,469,913 | £15,861,676 | £20,565,393 | +29.7% | |
| Operating profit | — | £383,459 | £388,481 | £529,915 | £370,630 | £4,235,885 | +1,042.9% | |
| Profit before tax | — | £378,770 | £388,481 | £2,898,981 | £410,529 | £4,199,012 | +922.8% | |
| Net profit | — | £68,961 | -£1,154 | £2,198,230 | £296,751 | £3,110,548 | +948.2% | |
| Cash | £468,874 | £834,264 | — | — | — | — | — | |
| Total assets less current liabilities | £6,947,595 | £10,347,616 | £11,897,796 | £4,748,400 | £5,045,150 | £8,378,925 | +66.1% | |
| Net assets | £6,947,595 | £10,347,616 | £11,897,796 | £4,748,400 | £5,045,150 | £8,155,592 | +61.7% | |
| Equity | £6,947,595 | £10,347,616 | £11,897,796 | £4,748,400 | £5,045,150 | £8,155,592 | +61.7% | |
| Average employees | 22 | 62 | 75 | 56 | 45 | 48 | +6.7% | |
| Wages | — | £6,658,937 | £7,923,703 | £6,244,667 | £5,009,421 | £5,953,156 | +18.8% | |
| Directors' remuneration | — | £206,384 | £418,202 | £16,614 | £0 | £307,867 | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2020-12-31 | 2021-12-31 | 2022-12-31 | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|---|---|---|
| Operating margin | — | 1.6% | 1.6% | 2.6% | 2.3% | 20.6% | |
| Net margin | — | 0.3% | -0.0% | 10.7% | 1.9% | 15.1% | |
| Return on capital employed | — | 3.7% | 3.3% | 11.2% | 7.3% | 50.6% | |
| Current ratio | — | — | — | 2.65x | 2.62x | 2.09x | |
| Interest cover | — | 81.78x | — | — | — | 73.77x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Name history
Renamed 4 times since incorporation — the current trading name was adopted 2024-10-01
- ALFASIGMA UK LIMITED 2024-10-01 → present
- GALAPAGOS BIOTECH LIMITED 2018-01-04 → 2024-10-01
- INPHARMATICA LIMITED 1998-08-24 → 2018-01-04
- INPHARMATICS LIMITED 1997-11-03 → 1998-08-24
- GAC NO.94 LIMITED 1997-07-08 → 1997-11-03
Audit & accounting basis
- Accounting basis
- FRS 102
- Auditor
- Deloitte Ireland LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“The directors have assessed the Company's ability to continue as a going concern and have a reasonable expectation that the Company has adequate resources to continue in operational existence for the foreseeable future. In doing this, they have considered the results for the period, expectations of future trading and the availability of continued funding. On the basis of this information the directors are satisfied that the Company will continue as a going concern and so the financial statements have been prepared on this basis.”
Significant events
- “After the reporting date, the directors approved a dividend of £4,500,000. As this dividend was declared after the reporting period, it has not been recognized as a liability at the reporting date. It is disclosed as a non-adjusting event in accordance with IAS 10 Events after the Reporting Period.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
1 active · 42 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| DE JONG, Marcel | Director | 2025-06-09 | Sep 1969 | Dutch |
Show 42 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| BANKS, Patrick John | Secretary | 2001-06-29 | 2007-03-21 |
| FILIUS, Bart | Secretary | 2021-12-06 | 2023-06-20 |
| HIRD, Sean Michael | Secretary | 1999-03-03 | 2001-06-29 |
| MAES, Xavier | Secretary | 2014-02-01 | 2021-07-30 |
| SINCLAIR, Neil | Secretary | 1998-06-24 | 1999-03-03 |
| VAN DEN EYNDE, Johan Gustaaf Cyriel | Secretary | 2007-03-21 | 2014-02-01 |
| ABBEY NOMINEES LIMITED | Corporate Secretary | 1997-07-08 | 1998-06-24 |
| ABI-SAAB, Walid Michael | Director | 2017-12-19 | 2022-12-31 |
| ALTSCHULER, David Simon | Director | 1998-03-16 | 2006-12-05 |
| BANKS, Patrick John | Director | 2001-06-29 | 2007-03-21 |
| BROWN, Kevin | Director | 2004-10-14 | 2006-12-05 |
| BULENS, Frank | Director | 1999-03-04 | 2006-12-05 |
| BUNTING, Stephen William, Dr | Director | 2001-09-26 | 2005-03-21 |
| CHAFFIN, Emma Rachel | Director | 2020-09-01 | 2023-01-31 |
| CUCCHI, Maria Chiara | Director | 2025-01-13 | 2026-04-28 |
| FILIUS, Bart | Director | 2016-01-01 | 2023-07-08 |
| GLEN, Robert Charles, Professor | Director | 1999-09-16 | 2001-06-29 |
| GREEN, Daniel Julian | Director | 2001-06-29 | 2004-10-14 |
| HIRD, Sean Michael | Director | 2000-01-25 | 2001-06-29 |
| JONES, David, Professor | Director | 1998-07-21 | 2001-06-29 |
| KITCHNER, Howard Edward | Director | 1998-07-21 | 2001-06-29 |
| LISLE, John Jerome | Director | 2004-11-01 | 2006-12-31 |
| LLOYD HARRIS, Quentin Lionel Genghis, Dr | Director | 2005-03-21 | 2006-12-05 |
| MAES, Xavier Marie Bernard Cecile | Director | 2018-05-24 | 2021-07-30 |
| MANTO, Michele | Director | 2021-12-06 | 2026-03-31 |
| MONCADA, Salvadore Enrique, Professor | Director | 1998-07-21 | 1999-03-04 |
| MOSES, Edwin, Dr | Director | 2001-06-29 | 2006-05-31 |
| NEWMAN, Stanton Peter, Professor | Director | 1998-07-21 | 1999-03-04 |
| NEWTON, Christopher Gregory, Dr | Director | 2006-12-21 | 2015-03-31 |
| NICHOL, Maria Zenarosa | Director | 2015-03-31 | 2015-12-31 |
| ORSATTI, Samara | Director | 2024-01-31 | 2025-01-13 |
| POWELL, Kenneth Leslie, Professor | Director | 1998-07-21 | 2001-06-29 |
| ROBERTS, Derek Harry, Sir | Director | 1998-07-21 | 2000-03-03 |
| ROSS, Barry Clive, Dr | Director | 2003-11-24 | 2006-07-11 |
| SEGAL, Anthony Walter, Professor | Director | 1998-07-21 | 2001-06-29 |
| SMITH, David Ross | Director | 2006-12-21 | 2007-05-31 |
| SOLOMON, Harry, Sir | Director | 1998-07-21 | 2004-10-14 |
| THORNTON, Janet Maureen, Professor Dame | Director | 1998-03-16 | 2001-06-29 |
| VAN DE STOLPE, Onno, Dr | Director | 2006-12-21 | 2022-03-31 |
| WEIR, Malcolm | Director | 2000-06-06 | 2006-07-05 |
| WIGERINCK, Piet Tom Bert | Director | 2017-12-19 | 2021-11-30 |
| ABBEY DIRECTORS LIMITED | Corporate Director | 1997-07-08 | 1998-03-16 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Andrea Golinelli | Individual | Significant influence | 2024-01-31 | Active |
| Stefano Golinelli | Individual | Significant influence | 2024-01-31 | Active |
| Galapagos Nv | Corporate entity | Shares 75–100% | 2016-04-06 | Ceased 2024-01-31 |
Filing timeline
Last 20 of 287 total filings
Material constitutional events — rename, articles re-file, resolution
- 2024-10-01 CERTNM Certificate change of name company PDF
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-07-09 | AA | accounts | Accounts with accounts type full | |
| 2026-05-22 | AP01 | officers | Appoint person director company with name date | |
| 2026-05-15 | AP01 | officers | Appoint person director company with name date | |
| 2026-04-28 | TM01 | officers | Termination director company with name termination date | |
| 2026-04-22 | TM01 | officers | Termination director company with name termination date | |
| 2026-04-09 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-12-17 | DISS40 | gazette | Gazette filings brought up to date | |
| 2025-12-16 | AA | accounts | Accounts with accounts type full | |
| 2025-12-02 | GAZ1 | gazette | Gazette notice compulsory | |
| 2025-06-25 | AP01 | officers | Appoint person director company with name date | |
| 2025-04-14 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-04-14 | CH01 | officers | Change person director company with change date | |
| 2025-04-11 | CH01 | officers | Change person director company with change date | |
| 2025-04-11 | CH01 | officers | Change person director company with change date | |
| 2025-03-03 | CH01 | officers | Change person director company with change date | |
| 2025-02-28 | AP01 | officers | Appoint person director company with name date | |
| 2025-02-25 | TM01 | officers | Termination director company with name termination date | |
| 2024-10-01 | CERTNM | change-of-name | Certificate change of name company | |
| 2024-07-18 | AA | accounts | Accounts with accounts type full | |
| 2024-04-05 | CS01 | confirmation-statement | Confirmation statement with updates |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 9
- Capital events
- 0
- Officers appointed
- 0
- Officers resigned
- 2
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.