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Cash

£792k

-49.1% vs 2024

Net assets

£2.4m

-38.8% lowest in 3 filed years

Employees

11

-21.4% lowest in 3 filed years

Profit before tax

-£2.4m

-13.4% lowest in 3 filed years

Watchouts

Facts from the Companies House register and the latest accounts — not a rating

Accounts

3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31

Metric Trend 2023-12-312024-12-312025-12-31 Δ vs prior
Turnover £9,600£49,775£31,372 -37%
Operating profit -£2,298,539-£2,141,671-£2,420,487 -13%
Profit before tax -£2,302,958-£2,130,455-£2,415,339 -13.4%
Net profit -£2,127,785-£2,002,759-£2,288,984 -14.3%
Cash £174,684£1,555,986£791,612 -49.1%
Total assets less current liabilities £2,915,784£3,917,083£2,396,522 -38.8%
Net assets £2,903,927£3,915,693£2,396,522 -38.8%
Equity £2,903,927£3,915,693£2,396,522 -38.8%
Average employees 161411 -21.4%
Wages £734,022£731,636£583,978 -20.2%
Directors' remuneration £318,454£373,870£300,310 -19.7%

Values shown as filed in the company's annual accounts. indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show . About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2023-12-312024-12-312025-12-31
Return on capital employed -78.8%-54.7%-101.0%
Gearing (liabilities / total assets) 7.2%8.1%8.9%
Current ratio 2.64x5.50x4.62x

Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.

Name history

Renamed 4 times since incorporation

  1. VALIRX PLC 2006-10-03 → present
  2. AZURE HOLDINGS PLC 2003-11-27 → 2006-10-03
  3. ROOM SERVICE GROUP PLC 2002-01-08 → 2003-11-27
  4. THE CUBE8 GROUP PLC 2001-06-14 → 2002-01-08
  5. CUBE8.COM PLC 2000-01-26 → 2001-06-14

Audit & accounting basis

Accounting basis
IFRS
Reporting scope
Consolidated group
Auditor
Adler Shine LLP
Audit opinion
Unqualified (clean)
Going concern
Material uncertainty disclosed

“The Board has referred to the fact that the Group and Parent Company are reliant on future fund raisings to continue their activities as budgeted. Should future fund raisings be unsuccessful, this may cast significant doubt on the Group and parent Company's ability to continue as a going concern.”

Group structure

  1. VALIRX PLC · parent
    1. ValiPharma Limited 100% · England & Wales · Therapeutic research & development
    2. ValiSeek Limited 55.55% · England & Wales · Therapeutic research & development
    3. Cytolytix Limited 60% · England & Wales · Therapeutic research & development
    4. Inaphaea BioLabs Limited 100% · England & Wales · Preclinical and drug discovery testing
    5. Blue Ribbon Bio Limited · England & Wales · Development of ValiRx Group assets in Prostate Cancer
    6. ValiRx Animal Health Limited · England & Wales · Development of ValiRx group Assets for companion animal applications
    7. ValiRx Bioinnovation Limited 100% · England & Wales · Intermediate holding company
    8. Valisrc Limited 100% · England & Wales · Dormant

Significant events

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

5 active · 43 resigned

Name Role Appointed Born Nationality
DESLER, Gerry Secretary 2022-06-30
DESLER, Gerry Director 2006-05-12 Jun 1945 British
ECCLESTON, Mark Edward, Dr Director 2024-08-12 Apr 1971 British
GOULDSTONE, Martin John Director 2024-04-22 Nov 1966 British
TRALAU-STEWART, Catherine Jane Director 2024-07-25 Aug 1963 British
Show 43 resigned officers
Name Role Appointed Resigned
ALEXANDER, Kevin John Secretary 2007-03-06 2022-06-30
BEVERLEY, Lucy Catherine Lindsey Secretary 2001-07-26 2002-01-07
MARSDEN, Philip Michael Secretary 2000-01-26 2000-12-04
SUMNER, Bernard Michael Secretary 2006-05-12 2007-03-06
SUMNER, Bernard Michael Secretary 2003-07-31 2006-03-01
TANG, Davy Secretary 2000-12-04 2001-07-26
CHILIOGON SECRETARIES LIMITED Corporate Secretary 2006-03-01 2006-05-12
PENNSEC LIMITED Corporate Secretary 2002-01-07 2003-06-12
SWIFT INCORPORATIONS LIMITED Corporate Nominee Secretary 2000-01-26 2000-01-26
ALEXANDER, Kevin John Director 2006-10-03 2022-06-30
BEVERLEY, Lucy Catherine Lindsey Director 2001-07-26 2002-01-07
COX, Kevin Paul Director 2020-06-26 2024-06-19
DE COURCEY, Adrian Michael Patrick Director 2024-04-22 2025-03-31
DE GIORGIO-MILLER, Oliver Director 2011-05-31 2019-10-21
DEAN SMITH, Timothy Director 2000-02-04 2002-01-07
DILLY, Suzanne Jane, Dr Director 2020-06-08 2024-08-15
DOBSON, David Director 2000-01-26 2002-01-07
DUMA, Alexander Agim Director 2002-01-07 2003-01-23
GOLD, Barry Director 2006-05-12 2006-10-03
GOLD, Gerald Stephen Director 2002-01-07 2004-10-07
GREENSTONE, Nicolas David Antony Director 2003-10-20 2006-05-12
HALLSWORTH, Jeremy Giles Director 2000-02-04 2001-03-30
HARDMAN, Norman, Dr Director 2008-09-01 2010-12-02
HARRIS, Raymond Ian Director 2003-10-20 2004-09-27
HINDSON, Brian Lee Director 2000-09-01 2002-01-09
KREIMEIA, Tarick Director 2001-05-02 2002-01-07
LAMPSHIRE, Martin Director 2020-05-07 2024-10-17
MAKINEN, Seppo Olavi Director 2013-10-04 2017-05-30
MASTERS, Stephen Director 2000-02-04 2002-01-07
MEISL, Alexander Thomas Joseph Director 2000-02-28 2000-12-31
MICALLEF, Jacob Vincent Director 2006-10-03 2010-09-30
MOORE, Anthony Roger Director 2006-10-03 2007-10-24
MORRIS, George Stephen, Dr Director 2006-10-03 2020-04-14
PANU, Stella Director 2022-10-11 2024-04-15
PARKER, Daniel Victor Elswood Director 2000-02-04 2001-04-11
PEARL, Ronald Stuart Director 2003-07-31 2003-10-20
PEARL, Ronald Stuart Director 2002-01-07 2003-03-10
STIRLING, Ronald Edward Director 2004-10-07 2006-05-12
THORNLEY, Nicholas James Director 2007-01-09 2013-10-04
VAINIKKA, Satu, Dr Director 2006-10-03 2020-04-14
WALTON, Susan Director 2000-02-04 2001-03-30
WINFIELD, John Kenrick Director 2000-02-16 2001-05-31
INSTANT COMPANIES LIMITED Corporate Nominee Director 2000-01-26 2000-01-26

Ownership

Persons with significant control

No persons with significant control on record.

Filing timeline

Last 20 of 402 total filings

Material constitutional events — rename, articles re-file, resolution

  • 2026-07-28 RESOLUTIONS Resolution
  • 2025-11-25 RESOLUTIONS Resolution
  • 2025-07-16 RESOLUTIONS Resolution
  • 2025-01-08 RESOLUTIONS Resolution
  • 2024-07-04 RESOLUTIONS Resolution
Date Type Category Description
2026-07-28 RESOLUTIONS resolution Resolution
2026-07-19 TM01 officers Termination director company with name termination date PDF
2026-07-04 AA accounts Accounts with accounts type group
2026-03-30 AD01 address Change registered office address company with date old address new address PDF
2026-01-31 SH01 capital Capital allotment shares PDF
2026-01-03 CS01 confirmation-statement Confirmation statement with no updates PDF
2025-11-25 RESOLUTIONS resolution Resolution
2025-11-21 SH01 capital Capital allotment shares PDF
2025-11-18 SH01 capital Capital allotment shares PDF
2025-07-16 RESOLUTIONS resolution Resolution
2025-06-17 AA accounts Accounts with accounts type group
2025-04-01 TM01 officers Termination director company with name termination date PDF
2025-01-26 CS01 confirmation-statement Confirmation statement with no updates PDF
2025-01-09 SH01 capital Capital allotment shares PDF
2025-01-08 RESOLUTIONS resolution Resolution
2024-10-19 TM01 officers Termination director company with name termination date PDF
2024-08-16 TM01 officers Termination director company with name termination date PDF
2024-08-12 AP01 officers Appoint person director company with name date PDF
2024-07-25 AP01 officers Appoint person director company with name date PDF
2024-07-04 RESOLUTIONS resolution Resolution

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
9

last 12 months

Capital events
4

last 24 months

Officers appointed
0

last 12 months

Officers resigned
0

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Official Companies House page