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Cash

£3.1m

USD 4,219,000

-42.7% lowest in 6 filed years

Net assets

£28m

USD 38,154,000

+177.2% highest in 6 filed years

Employees

14

0% vs 2024

Profit before tax

-£23m

USD -31,177,000

-148.2% lowest in 6 filed years

Accounts

6-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31

Metric Trend 2020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31 Δ vs prior
Turnover £92,675,000£110,700,000£76,426,000£39,056,856£38,123,374£30,430,323 -20.2%
Operating profit -£14,045,000£1,082,000-£9,134,000-£17,433,668-£7,311,037-£19,975,474 -173.2%
Profit before tax -£14,687,000£259,000-£8,806,000-£16,981,791-£9,334,077-£23,171,312 -148.2%
Net profit -£15,019,000-£200,000-£9,153,000-£18,470,457-£9,785,953-£21,215,162 -116.8%
Cash £18,933,000£9,004,000£37,179,000£8,425,121£5,476,031£3,135,637 -42.7%
Total assets less current liabilities -£2,716,000-£2,916,000-£12,069,000-£27,065,032-£36,745,448£28,356,745 +177.2%
Net assets -£2,716,000-£2,916,000-£12,069,000-£27,065,032-£36,745,448£28,356,745 +177.2%
Equity -£2,716,000-£2,916,000-£12,069,000-£27,065,032-£36,745,448£28,356,745 +177.2%
Average employees 422018151414 0%
Wages £3,600,000£2,164,000£1,393,000£1,099,220£1,045,708£1,341,509 +28.3%
Directors' remuneration £189,000£144,000

Figures converted to GBP from USD at 0.743 per USD (Frankfurter spot rate) — hover any figure for the original. indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show . About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Operating margin -15.2%1.0%-12.0%-44.6%-19.2%-65.6%
Net margin -16.2%-0.2%-12.0%-47.3%-25.7%-69.7%
Return on capital employed -70.4%
Current ratio 0.43x0.38x1.49x
Interest cover -11.76x0.91x-27.51x-66.83x-3.03x-5.84x

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.

Name history

Renamed 1 time since incorporation

  1. SYNEXUS CLINICAL RESEARCH LIMITED 2008-06-30 → present
  2. SYNEXUS CLINICAL RESEARCH PLC 2005-09-27 → 2008-06-30

Audit & accounting basis

Accounting basis
FRS 102
Reporting scope
Standalone (parent only)
Auditor
Mitchell Charlesworth (Audit) Limited
Audit opinion
Unqualified (clean)
Going concern
Affirmed

“The directors have a reasonable expectation that the Company has adequate resources to continue in operational existence for the foreseeable future. They adopt the going concern basis, relying on the ongoing support of the parent group. Thermo Fisher Scientific Inc confirmed it intends to support the company for at least 12 months after financial statements approval.”

Group structure

  1. SYNEXUS CLINICAL RESEARCH LIMITED · parent
    1. Synexus Limited 100% · UK · Clinical trials
    2. Synexus Polska sp z.o.o 100% · Poland · Clinical trials
    3. Synexus Clinical Research SA (Pty) Limited 100% · South Africa · Clinical trials
    4. Synexus Magyarorszag Kft 100% · Hungary · Clinical trials
    5. Synexus Clinical Research GmbH 100% · Germany · Clinical trials
    6. Synexus Ukraine Limited Liability Company 100% · Ukraine · Clinical trials
    7. Synexus Bulgaria 100% · Bulgaria · Clinical trials
    8. Medical Centre Synexus Sofia EOOD* 100% · Bulgaria · Clinical trials
    9. Synexus Czeh s.r.o 100% · Czech Republic · Clinical trials

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

6 active · 29 resigned

Name Role Appointed Born Nationality
OAKWOOD CORPORATE SECRETARY LIMITED Corporate Secretary 2022-11-29
AHMED, Syed Waqas Director 2023-03-29 Nov 1979 British
CAMERON, Euan Daney Ross Director 2023-03-29 Mar 1976 British
GREEN, Georgina Adams Director 2024-04-18 Mar 1970 British
SMITH, Anthony Hugh Director 2023-03-29 May 1962 American
STARR, Alison Jane Director 2024-04-18 Jan 1977 British
Show 29 resigned officers
Name Role Appointed Resigned
GREGG, Rhona Secretary 2022-11-29 2026-03-31
MCCLUSKEY, Paul Secretary 2007-06-28 2011-06-30
NEILSON, Christopher Secretary 2005-09-27 2006-09-04
HALLIWELLS SECRETARIES LIMITED Corporate Nominee Secretary 2006-09-04 2007-06-28
SECRETARIAL APPOINTMENTS LIMITED Corporate Nominee Secretary 2005-09-27 2005-09-27
BERG, Jason James Director 2023-01-31 2023-03-29
BERTHOUX, Christophe Director 2010-09-13 2016-05-31
BOYCE, Alan James Director 2007-02-19 2008-03-31
CHAMBERS, Paul Michael Director 2016-10-18 2017-10-10
CHAMBERS, Paul Michael Director 2011-09-23 2016-05-31
FORT, Michael John Director 2005-09-27 2011-04-08
GONDEK, Marcin Director 2017-10-10 2019-09-13
HARRIS, Richard Stuart Director 2021-06-30 2023-03-29
HARTMAN, Brainard Judd Director 2016-05-31 2019-09-13
HUGHES, Malcolm Keith Director 2006-06-06 2007-12-05
JAMES, Julia Mary Director 2016-05-31 2023-05-24
MCCLUSKEY, Paul Director 2006-09-18 2011-06-30
MISCAMPBELL, Ian Alexander Francis Director 2005-10-01 2007-12-05
NEILD, Christopher David Director 2016-05-31 2020-03-19
NEILSON, Christopher Director 2005-09-27 2006-09-15
NORMAN, David John Director 2023-03-29 2024-04-18
OWEN, Dustin Nathan Director 2021-06-30 2023-01-31
PELLEGRINO, Jill Marie Director 2020-06-30 2021-06-30
REDMOND, Michael Director 2005-09-27 2007-07-19
SMITH, Ian Geoffrey Director 2005-09-27 2007-12-05
SMITH, Roger Dale Director 2019-09-12 2020-06-30
TONDER, Riaan Van Director 2019-09-12 2021-06-30
CORPORATE APPOINTMENTS LIMITED Corporate Nominee Director 2005-09-27 2005-09-27
SECRETARIAL APPOINTMENTS LIMITED Corporate Nominee Director 2005-09-27 2007-12-05

Ownership

Persons with significant control

Name Kind Nature of control Notified Status
Synexus Clinical Research Midco No 1 Limited Corporate entity Shares 75–100%, Voting 75–100%, Appoints directors 2016-08-31 Active
Synexus Clinical Research Acquisitions Limited Corporate entity Shares 75–100%, Voting 75–100%, Appoints directors 2016-04-06 Ceased 2016-08-31
Synexus Clinical Research Acquisitions Limited Corporate entity Shares 75–100%, Voting 75–100%, Appoints directors 2016-04-06 Ceased 2016-08-31

Filing timeline

Last 20 of 214 total filings

Material constitutional events — rename, articles re-file, resolution

  • 2025-12-30 RESOLUTIONS Resolution
  • 2025-12-20 RESOLUTIONS Resolution
  • 2025-12-20 RESOLUTIONS Resolution
Date Type Category Description
2026-07-13 AA accounts Accounts with accounts type full
2026-06-23 CS01 confirmation-statement Confirmation statement with updates PDF
2026-04-01 TM02 officers Termination secretary company with name termination date PDF
2026-01-30 SH19 capital Capital statement capital company with date currency figure
2025-12-30 SH19 capital Capital statement capital company with date currency figure
2025-12-30 SH20 capital Legacy
2025-12-30 CAP-SS insolvency Legacy
2025-12-30 RESOLUTIONS resolution Resolution
2025-12-20 RESOLUTIONS resolution Resolution
2025-12-20 RESOLUTIONS resolution Resolution
2025-12-19 SH01 capital Capital allotment shares PDF
2025-07-28 AA accounts Accounts with accounts type full
2025-06-23 CS01 confirmation-statement Confirmation statement with no updates PDF
2024-11-11 AA accounts Accounts with accounts type full
2024-06-24 CS01 confirmation-statement Confirmation statement with no updates PDF
2024-04-23 AP01 officers Appoint person director company with name date PDF
2024-04-19 AP01 officers Appoint person director company with name date PDF
2024-04-19 TM01 officers Termination director company with name termination date PDF
2023-12-20 AA accounts Accounts with accounts type full PDF
2023-06-23 CS01 confirmation-statement Confirmation statement with no updates PDF

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
11

last 12 months

Capital events
4

last 24 months

Officers appointed
0

last 12 months

Officers resigned
1

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Official Companies House page