WAVE LIFE SCIENCES UK LIMITED
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Cash
£7.7m
USD 10,312,000
+85.6% vs 2024
Net assets
-£30m
USD -39,861,000
-2.5% vs 2024
Employees
12
0% vs 2024
Profit before tax
-£50m
USD -67,618,000
-122.2% vs 2024
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Negative shareholders' funds
Net assets
2-year trend · vs Health Care median
Accounts
2-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|
| Turnover | £38,790,194 | £14,268,646 | -63.2% | |
| Operating profit | -£23,676,377 | -£50,717,625 | -114.2% | |
| Profit before tax | -£22,579,592 | -£50,180,334 | -122.2% | |
| Net profit | -£18,215,536 | -£50,110,575 | -175.1% | |
| Cash | £4,122,891 | £7,652,690 | +85.6% | |
| Total assets less current liabilities | -£26,672,238 | -£26,977,365 | -1.1% | |
| Net assets | -£28,856,256 | -£29,581,447 | -2.5% | |
| Equity | — | — | — | |
| Average employees | 12 | 12 | 0% | |
| Wages | £2,978,351 | £2,833,395 | -4.9% | |
| Directors' remuneration | £636,740 | £445,269 | -30.1% | |
| Highest paid director | £238,777 | £222,635 | -6.8% |
Figures converted to GBP from USD at 0.742 per USD (Frankfurter spot rate) — hover any figure for the original. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2024-12-31 | 2025-12-31 |
|---|---|---|---|
| Operating margin | -61.0% | — | |
| Net margin | -47.0% | — | |
| Gearing (liabilities / total assets) | 336.3% | 319.6% | |
| Current ratio | 0.31x | 0.33x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Standalone (parent only)
- Auditor
- KPMG LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“Consequently, the directors are confident that the Company will have sufficient funds to continue to meet its liabilities as they fall due for at least 12 months from the date of approval of the financial statements and have prepared the financial statements on a going concern basis.”
Significant events
- “On 2 February 2026, the Company announced that it regained full rights to WVE-006, an investigational GalNAc-conjugated RNA editing oligonucleotide for alpha-1 antitrypsin deficiency...”
- “On 17 January 2025, the Company issued one ordinary share with par value of £1 ($1.22) for total consideration of £25.0 million ($30.5 million)...”
- “On 21 May 2025, the Company issued one ordinary share with par value of £1 ($1.34) for total consideration of £25.0 million ($33.4 million)...”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
3 active · 5 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BOLNO, Paul B. | Director | 2017-04-03 | Mar 1974 | American |
| MORAN, Kyle Brendan | Director | 2025-10-23 | Apr 1970 | American |
| ROCKETT, Linda | Director | 2017-04-03 | Mar 1972 | American |
Show 5 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| PETERSHILL SECRETARIES LIMITED | Corporate Secretary | 2017-04-03 | 2026-03-25 |
| FRANCIS, Christopher John | Director | 2017-09-06 | 2018-02-07 |
| LI-KWAI-CHEUNG, Anne-Marie | Director | 2022-10-14 | 2024-12-24 |
| PANZARA, Michael, Dr | Director | 2018-02-07 | 2022-10-14 |
| REGNANTE, Keith C. | Director | 2017-04-03 | 2017-09-06 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Wave Life Sciences Ltd. | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2017-04-03 | Active |
Filing timeline
Last 20 of 48 total filings
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-09-15 | AA | accounts | Accounts with accounts type full | |
| 2026-04-30 | PSC05 | persons-with-significant-control | Change to a person with significant control | |
| 2026-04-30 | SH01 | capital | Capital allotment shares | |
| 2026-04-17 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2026-04-15 | TM02 | officers | Termination secretary company with name termination date | |
| 2026-01-29 | SH01 | capital | Capital allotment shares | |
| 2025-11-10 | AP01 | officers | Appoint person director company with name date | |
| 2025-07-10 | AA | accounts | Accounts with accounts type small | |
| 2025-05-28 | SH01 | capital | Capital allotment shares | |
| 2025-04-11 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-01-27 | SH01 | capital | Capital allotment shares | |
| 2025-01-02 | TM01 | officers | Termination director company with name termination date | |
| 2024-05-07 | AA | accounts | Accounts with accounts type small | |
| 2024-04-16 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2024-02-01 | SH01 | capital | Capital allotment shares | |
| 2023-07-04 | AA | accounts | Accounts with accounts type small | |
| 2023-04-06 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2023-01-06 | CH04 | officers | Change corporate secretary company with change date | |
| 2022-12-19 | SH01 | capital | Capital allotment shares | |
| 2022-11-04 | TM01 | officers | Termination director company with name termination date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 7
- Capital events
- 4
- Officers appointed
- 1
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.