ISTESSO LIMITED
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Cash
£4.9M
-2% lowest in 3 filed years
Net assets
-£28M
+4.3% vs 2024
Employees
11
-26.7% lowest in 3 filed years
Profit before tax
£78K
+100.9% highest in 3 filed years
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Negative shareholders' funds
Net assets
3-year trend · vs Industrials median
Accounts
3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|
| Turnover | — | £61,516 | — | — | |
| Operating profit | -£19,118,938 | -£11,580,842 | -£4,185,766 | +63.9% | |
| Profit before tax | -£17,386,116 | -£8,334,684 | £77,738 | +100.9% | |
| Net profit | -£14,963,408 | -£7,058,455 | £1,031,367 | +114.6% | |
| Cash | £5,475,983 | £5,024,682 | £4,922,391 | -2% | |
| Total assets less current liabilities | — | — | — | — | |
| Net assets | -£22,055,036 | -£28,762,955 | -£27,516,017 | +4.3% | |
| Equity | — | — | — | — | |
| Average employees | 13 | 15 | 11 | -26.7% | |
| Wages | £1,422,788 | £1,878,263 | £1,412,585 | -24.8% | |
| Directors' remuneration | £388,551 | £820,204 | £664,427 | -19% |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|
| Gearing (liabilities / total assets) | 324.2% | 415.6% | 542.4% | |
| Current ratio | 6.90x | 15.13x | 10.93x | |
| Interest cover | -32.18x | -3.93x | -0.54x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- UK-adopted IFRS
- Reporting scope
- Consolidated group
- Auditor
- Saffrey LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“In conclusion, the financial statements have been prepared on a going concern basis and do not include any adjustments that would result if the Group was not able to continue as a going concern.”
Group structure
- ISTESSO LIMITED · parent
- PIMCO 2664 Limited 100%
- Modern Biosciences Nominees Limited* 100%
- Istesso Therapeutics Limited 100%
- MBS4 Limited 100%
- MBS5 Limited 100%
- Istesso Europe Limited* 100%
- Istesso 1 Limited* 100%
- Istesso 2 Limited* 100%
- Istesso 3 Limited* 100%
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
7 active · 2 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| PINSENT MASONS SECRETARIAL LIMITED | Corporate Secretary | 2017-09-12 | — | — |
| ALLEN, Peter Vance | Director | 2017-09-01 | Mar 1956 | British |
| OWEN, Michael, Dr | Director | 2025-06-01 | May 1951 | British |
| PATEL, Lisa, Dr | Director | 2017-05-05 | May 1973 | British |
| PETERS, David Keith, Professor Sir | Director | 2017-09-01 | Jul 1938 | British |
| WILLIAMS, Samuel Cameron, Dr | Director | 2017-05-05 | Apr 1969 | British |
| IP2IPO SERVICES LIMITED | Corporate Director | 2025-07-02 | — | — |
Show 2 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| IP2IPO SERVICES LIMITED | Corporate Secretary | 2017-05-05 | 2017-09-12 |
| IP2IPO SERVICES LIMITED | Corporate Director | 2017-05-05 | 2017-12-22 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Ip2ipo Limited | Corporate entity | Shares 25–50%, Voting 25–50% | 2018-09-18 | Active |
| Ip Group Plc | Corporate entity | Shares 25–50%, Voting 25–50% | 2017-06-30 | Ceased 2018-09-18 |
| Samuel Cameron Williams | Individual | Shares 75–100%, Voting 75–100%, Appoints directors | 2017-05-05 | Ceased 2017-06-30 |
Filing timeline
Last 20 of 63 total filings
Material constitutional events — rename, articles re-file, resolution
- 2023-08-21 RESOLUTIONS Resolution
- 2023-08-21 MA Memorandum articles
- 2023-05-27 RESOLUTIONS Resolution
- 2023-05-16 MA Memorandum articles
- 2023-05-16 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-06-08 | AA | accounts | Accounts with accounts type group | |
| 2026-05-08 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2026-02-05 | SH01 | capital | Capital allotment shares | |
| 2026-01-26 | SH01 | capital | Capital allotment shares | |
| 2025-11-17 | SH01 | capital | Capital allotment shares | |
| 2025-09-16 | AA | accounts | Accounts with accounts type group | |
| 2025-07-02 | AP02 | officers | Appoint corporate director company with name date | |
| 2025-06-13 | AP01 | officers | Appoint person director company with name date | |
| 2025-05-19 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-01-03 | AA | accounts | Accounts with accounts type group | |
| 2024-05-15 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-05-15 | PSC05 | persons-with-significant-control | Change to a person with significant control | |
| 2023-12-22 | AA | accounts | Accounts with accounts type group | |
| 2023-08-21 | RESOLUTIONS | resolution | Resolution | |
| 2023-08-21 | MA | incorporation | Memorandum articles | |
| 2023-05-27 | RESOLUTIONS | resolution | Resolution | |
| 2023-05-19 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2023-05-16 | MA | incorporation | Memorandum articles | |
| 2023-05-16 | RESOLUTIONS | resolution | Resolution | |
| 2023-05-03 | SH01 | capital | Capital allotment shares |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 7
- Capital events
- 3
- Officers appointed
- 1
- Officers resigned
- 0
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.